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Studies involving animals 2
2024;4:5571 DOI: Received: September 18, 2023 Accepted: December 19, 2023 Published: February 27, 2024 Academic Editor: Silvia Fischer, Justus-Liebig-University, Germany The article belongs to the special issue Therapeutic Targets for Neuroprotection in Ischemic Stroke Acute ischemic stroke (AIS) is the leading cause of disability worldwide, and recanalization therapy is significant in the hyperacute phase of AIS
A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development
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BPC-157 and similar compounds tested in horses with generally positive results
